全文获取类型
收费全文 | 63022篇 |
免费 | 7305篇 |
国内免费 | 2101篇 |
专业分类
电工技术 | 2397篇 |
综合类 | 2364篇 |
化学工业 | 14417篇 |
金属工艺 | 3711篇 |
机械仪表 | 3807篇 |
建筑科学 | 4494篇 |
矿业工程 | 1616篇 |
能源动力 | 1655篇 |
轻工业 | 6741篇 |
水利工程 | 1019篇 |
石油天然气 | 1572篇 |
武器工业 | 326篇 |
无线电 | 8058篇 |
一般工业技术 | 9703篇 |
冶金工业 | 2759篇 |
原子能技术 | 800篇 |
自动化技术 | 6989篇 |
出版年
2024年 | 103篇 |
2023年 | 1114篇 |
2022年 | 2184篇 |
2021年 | 3712篇 |
2020年 | 1930篇 |
2019年 | 1963篇 |
2018年 | 2153篇 |
2017年 | 2772篇 |
2016年 | 3946篇 |
2015年 | 4393篇 |
2014年 | 4897篇 |
2013年 | 4702篇 |
2012年 | 3566篇 |
2011年 | 3528篇 |
2010年 | 2612篇 |
2009年 | 2742篇 |
2008年 | 2613篇 |
2007年 | 3635篇 |
2006年 | 3850篇 |
2005年 | 3196篇 |
2004年 | 2192篇 |
2003年 | 2092篇 |
2002年 | 1545篇 |
2001年 | 862篇 |
2000年 | 694篇 |
1999年 | 763篇 |
1998年 | 590篇 |
1997年 | 563篇 |
1996年 | 578篇 |
1995年 | 395篇 |
1994年 | 412篇 |
1993年 | 299篇 |
1992年 | 243篇 |
1991年 | 224篇 |
1990年 | 227篇 |
1989年 | 189篇 |
1988年 | 123篇 |
1987年 | 77篇 |
1986年 | 69篇 |
1985年 | 63篇 |
1984年 | 71篇 |
1983年 | 49篇 |
1982年 | 46篇 |
1981年 | 40篇 |
1980年 | 49篇 |
1966年 | 25篇 |
1964年 | 34篇 |
1962年 | 64篇 |
1959年 | 21篇 |
1955年 | 23篇 |
排序方式: 共有10000条查询结果,搜索用时 78 毫秒
31.
Saerom Lee Ga-Eun Lim Yong-Nyun Kim Hyeon-Sook Koo Jaegal Shim 《International journal of molecular sciences》2021,22(4)
The extracellular matrix (ECM) is important for normal development and disease states, including inflammation and fibrosis. To understand the complex regulation of ECM, we performed a suppressor screening using Caenorhabditis elegans expressing the mutant ROL-6 collagen protein. One cuticle mutant has a mutation in dpy-23 that encodes the μ2 adaptin (AP2M1) of clathrin-associated protein complex II (AP-2). The subsequent suppressor screening for dpy-23 revealed the lon-2 mutation. LON-2 functions to regulate body size through negative regulation of the tumor growth factor-beta (TGF-β) signaling pathway responsible for ECM production. RNA-seq analysis showed a dominant change in the expression of collagen genes and cuticle components. We noted an increase in the cav-1 gene encoding caveolin-1, which functions in clathrin-independent endocytosis. By knockdown of cav-1, the reduced TGF-β signal was significantly restored in the dpy-23 mutant. In conclusion, the dpy-23 mutation upregulated cav-1 expression in the hypodermis, and increased CAV-1 resulted in a decrease of TβRI. Finally, the reduction of collagen expression including rol-6 by the reduced TGF-β signal influenced the cuticle formation of the dpy-23 mutant. These findings could help us to understand the complex process of ECM regulation in organism development and disease conditions. 相似文献
32.
33.
When a laser beam induces surface tension gradient at the free surface of a liquid, a weak surface depression is expected and has been observed. Here we report giant depression and rupture in “optothermocapillary fluids” under the illumination of laser and sunlight. Computational fluid dynamics models were developed to understand the surface deformation and provided desirable physical parameters of the fluid for maximum deformation. New optothermocapillary fluids were created by mixing transparent lamp oil with different candle dyes. They can be cut open by sunlight and be patterned to different shapes and sizes using an ordinary laser show projector or a common laser pointer. Laser driving and elevation of optothermocapillary fluids, in addition to the manipulation of different droplets on their surface, were demonstrated as an efficient controlling method and platform for optofluidic operations. The fundamental understanding of light-induced giant depression and creation of new optothermocapillary fluids encourage the fundamental research and applications of optofluidics. 相似文献
34.
Siyao Li Shoulei Xu Xiangyu Wang Daini Wang Bernard A. Goodman Xing Hong Wen Deng 《Ceramics International》2021,47(3):3346-3353
Cubic zirconia single crystals stabilized with yttria and doped with Gd2O3 (0.10–5.00 mol%) were prepared by the optical floating zone method, and characterized by a combination of X-ray diffraction (XRD), and Raman, electron paramagnetic resonance (EPR), ultraviolet–visible (UV–Vis), photoluminescence excitation (PLE) and photoluminescence (PL) spectroscopic techniques. XRD and Raman spectroscopy showed that the crystal samples were all in the cubic phase, whereas the ceramic sample consisted of a mixture of monoclinic and cubic phases. The absorption spectrum showed four peaks at 245, 273, 308, and 314 nm in the ultraviolet region, and the optical band gap differed between samples with ≤3.00 mol% and those with >3.00 mol% Gd2O3. The emission spectrum showed a weak peak at 308 nm and a strong peak at 314 nm, which are attributed to the 6P5/2 → 8S7/2 and 6P7/2 → 8S7/2 transitions of Gd3+, respectively. The intensities of the peaks in the excitation and emission spectra increased with Gd3+ concentration, reached a maximum at 2.00 mol%, then decreased with higher concentrations. This quenching is considered to be the result of the electric dipole-dipole interactions, and this interpretation is supported by the Gd3+ EPR spectra, which showed progressive broadening with increasing Gd3+ concentration throughout the concentration range investigated. 相似文献
35.
Constantin Tnase Lucia Pintilie Raluca Elena Tnase 《International journal of molecular sciences》2021,22(4)
In the total stereo-controlled synthesis of natural prostaglandins (PGs) and their structural analogs, a vast class of compounds and drugs, known as the lactones, are encountered in a few key steps to build the final molecule, as: δ-lactones, γ-lactones, and 1,9-, 1,11-, and 1,15-macrolactones. After the synthesis of 1,9-PGF2α and 1,15-PGF2α lactones, many 1,15-lactones of E2, E3, F2, F3, A2, and A3 were found in the marine mollusc Tethys fimbria and the quest for understanding their biological role stimulated the research on their synthesis. Then 1,9-, 1,11-, and 1,15-PG lactones of the drugs were synthesized as an alternative to the corresponding esters, and the first part of the paper describes the methods used for their synthesis. The efficient Corey procedure for the synthesis of prostaglandins uses the key δ-lactone and γ-lactone intermediates with three or four stereocenters on the cyclopentane fragment to link the PG side chains. The paper describes the most used procedures for the synthesis of the milestone δ-Corey-lactones and γ-Corey-lactones, their improvements, and some new promising methods, such as interesting, new stereo-controlled and catalyzed enantioselective reactions, and methods based on the chemical/enzymatic resolution of the compounds in different steps of the sequences. The many uses of δ-lactones not only for the synthesis of γ-lactones, but also for obtaining 9β-halogen-PGs and halogen-substituted cyclopentane intermediates, as synthons for new 9β-PG analogs and future applications, are also discussed. 相似文献
36.
Eugene Metakovsky Laura Pascual Patrizia Vaccino Viktor Melnik Marta Rodriguez-Quijano Yulia Popovych Sabina Chebotar William John Rogers 《International journal of molecular sciences》2021,22(4)
The Gli-B1-encoded γ-gliadins and non-coding γ-gliadin DNA sequences for 15 different alleles of common wheat have been compared using seven tests: electrophoretic mobility (EM) and molecular weight (MW) of the encoded major γ-gliadin, restriction fragment length polymorphism patterns (RFLPs) (three different markers), Gli-B1-γ-gliadin-pseudogene known SNP markers (Single nucleotide polymorphisms) and sequencing the pseudogene GAG56B. It was discovered that encoded γ-gliadins, with contrasting EM, had similar MWs. However, seven allelic variants (designated from I to VII) differed among them in the other six tests: I (alleles Gli-B1i, k, m, o), II (Gli-B1n, q, s), III (Gli-B1b), IV (Gli-B1e, f, g), V (Gli-B1h), VI (Gli-B1d) and VII (Gli-B1a). Allele Gli-B1c (variant VIII) was identical to the alleles from group IV in four of the tests. Some tests might show a fine difference between alleles belonging to the same variant. Our results attest in favor of the independent origin of at least seven variants at the Gli-B1 locus that might originate from deeply diverged genotypes of the donor(s) of the B genome in hexaploid wheat and therefore might be called “heteroallelic”. The donor’s particularities at the Gli-B1 locus might be conserved since that time and decisively contribute to the current high genetic diversity of common wheat. 相似文献
37.
Jinchen Wei Lilai Jiang Menglin Huang Yuning Wu Shiyou Chen 《Advanced functional materials》2021,31(42):2104913
It is believed that promoting the fraction of ferroelectric orthorhombic phase (o-phase) through O-poor growth conditions can increase the spontaneous polarization of HfO2 and (Hf,Zr)O2 thin films. However, the first-principles calculations show that the growth may be limited by the easy formation of point defects in the orthorhombic and tetragonal phases of HfO2, ZrO2, and (Hf,Zr)O2. Their dominant defects, O interstitial (Oi) under O-rich conditions and O vacancy (VO) under O-poor condition, have low formation energies and quite high density (1016–1019 cm−3 for 800–1400 K growth temperature). Especially, Oi has negative formation energy in tetragonal HfO2 under O-rich condition, causing non-stoichiometry and limiting the crystalline-seed formation during o-phase growth. High-density defects can cause disordering of dipole moments and increase leakage current, both diminishing the polarization. These results explain the experimental puzzle that the measured polarization is much lower than the ideal value even in O-poor thin films and highlight that controlling defects is as important as promoting the o-phase fraction for enhancing ferroelectricity. The O-intermediate condition (average of O-rich and O-poor conditions) and low growth temperature are proposed for fabricating HfO2 and (Hf,Zr)O2 with fewer defects, lower leakage current, and stronger ferroelectricity, which challenges the belief that O-poor condition is optimal. 相似文献
38.
Housei Akazawa 《Ceramics International》2021,47(3):3292-3298
Undoped and Er3+-doped Bi2O3 thin films were sputter-deposited on Si(100) substrates. Sufficiently oxidized Bi2O3 films with refractive indices between 2.17?2.23 were obtained at a wavelength of 633 nm; these values are comparable to those of bulk Bi2O3 crystals. While the film composition was stable for deposition temperatures between room temperature (RT) and 450 °C, the refractive index steeply decreased above 450 °C and reached 1.4 at 600 °C. The lowering of the optical transmittance spectra indicated aggregation of metallic Bi and darkening of the film. All films exhibited X-ray diffraction patterns of α-Bi2O3. The direct and indirect bandgap energies derived from the Tauc plots were 3.4–3.7 eV and 1.9–2.5 eV, respectively, depending on the O2 flow rate and deposition temperature. Upon excitation of Er3+-doped Bi2O3 films at 532 nm, Er3+ emissions peaking at 1537 and 1541 nm appeared, and the photoluminescence spectra included fine structures reflecting crystal-field splitting. Resonant excitation of Er3+ 4f levels and indirect excitation via the defect levels of Bi2O3 followed by energy transfer to Er3+ contributed to the emission. The films deposited at RT with Er concentrations of 2 at.% had the emission intensity of Er3+, but concentration quenching strongly suppressed the Er3+ emission because the doped Er3+ ions stayed inside the Bi2O3 crystals. At deposition temperatures above 400 °C, the concentration quenching was mitigated possibly because out-diffusion of Er3+ ions reduced the effective number of Er3+ ions in the Bi2O3 crystalline domains. 相似文献
39.
《Ceramics International》2022,48(15):21773-21780
In this work, Ni/TiC composites were synthesized by the laser cladding technique (LCT). A scanning electron microscope (SEM), X-ray diffractometer (XRD), microhardness meter, electrochemical workstation, and friction and wear tester examined the microstructure, surface morphology, phase structure, microhardness, wear, and corrosion resistances of the Ni/TiC composites. These results indicated the Ni/40TiC composite contained finer equiaxed crystals than the Ni and Ni/20TiC composites. In addition, numerous TiC particles in the Ni/40TiC composite impeded growth of the nickel crystals, which resulted in the fine microstructure of the Ni/40TiC composite. The Ni, Ni/20TiC, and Ni/40TiC composites exhibited face-centered cubic (f c c) lattices. The average microhardness values of the Ni/20TiC and Ni/40TiC composites were approximately 748 HV and 851 HV, respectively. The Ni/40TiC composite had the lowest friction coefficient (0.43) among all three coatings, and only some shallow scratches appeared on the surface of the Ni/40TiC composite. The corrosion potential (E) of Ni/40TiC exceeded the Ni/20TiC composite, and both were larger than the Ni composite, which indicated the Ni/40TiC composite had outstanding corrosion resistance and the Ni composite had poor corrosion resistance. The corrosion current densities (i) of Ni, Ni/20TiC, and Ni/40TiC composites were 5.912, 4.405, and 3.248 μA/cm2, respectively. 相似文献
40.
《Ceramics International》2022,48(5):6294-6301
Materials with high thermo mechanical properties are required as laser media for high-powered lasers. One of such materials is lutetium-aluminum garnet (LuAG) doped with ytterbium. In the present work, we discuss for the first time a full comparative study of 5% Yb-doped LuYAG ceramics with variation Lu/Y ratio. Samples were prepared with addition of B2O3, MgO and SiO2 which were used as sintering aids. Grain sizes, shrinkage curves, lattice constants and transmission spectra were measured for all samples. Thermal conductivity was measured in a wide temperature range for all studied samples. Output power of 12 W and 60% slope efficiency were obtained on the 5% Yb:LuAG disk laser. 相似文献